Ученые Института гидробиологии и экологии изучают морфологическое разнообразие и закономерности роста отолитов рыб для оценки питания каспийского тюленя (Pusa caspica) в периоды залегания на лежбищах.
Реферат: This study was conducted to evaluate the one-year survival rate of patients with primary malignant central nervous system (CNS) tumors after surgical treatment in Kazakhstan. Retrospective data of patients undergoing operations in the Department of Central Nervous System Pathology in the JSC National Centre for Neurosurgery in the period from 2009 to 2011 were used as the research material. Kaplan-Meier survival analysis was performed with the following information: gender, date of birth, place of residence, diagnosis according to ICD-10, the date of the operation, the morphological type of tumor, clinical stage, state at the end of the first year of observation, and the date of death. The study was approved by the ethical committee of the JSC National Centre for Neurosurgery. The overall one-year overall survival rate (n=152) was 56.5% (95% confidence interval (CI): 50.2-62.7), and 79.5% (95% CI 72.2-86.8) and 33.1% (95% CI: 21.0-42.3) for Grades I-II (n=76) and Grades III-IV (n=76), respectively. Significant prognostic factors which affected the survival rate were age and higher tumor grade (Grades III-IV), corresponding with results described elsewhere in the world.
Epidemiological Assessment of Leukemia in Kazakhstan, 2003-2012
Реферат: Cancer is a major health problem facing the entire world, and Kazakhstan is not the exception. The aim of this study was to present an epidemiological assessment of leukemia in the population of Kazakhstan during 2003-2012. This descriptive and retrospective study was based on data obtained from all oncological organizations of the whole country. Age standardized incidence rates per 100,000 population for leukemia were calculated. Totally, 6,741 new cases of leukemia were registered in Kazakhstan during the 10 year period. The mean age of patients with leukemia was 48.5. The ASRs for leukemia among men and women were 5.3 and 3.6, respectively (p<0.001). In conclusion, our results showed a high incidence rate of leukemia in Kazakhstan, especially in the north of the country. The incidence of leukemia was significantly higher in males and increased with age. Determining and controlling important risk factors of leukemia may lead to decrease in its burden.
Behcet\'s disease in HLA-B*51 negative Germans and Turks shows association with HLA-Bw4-80I
Автор(ы): Kuranov A. B.*Kotter I.*Henes J. Ch.*Abisheva S. T.*Steiert I.*Riewerts F.*Momynaliev K. T.*Muller C. A.*
Реферат: Behcet\'s disease (BD) as systemic vasculitis of unknown etiology is associated with HLA-B*51 in European and Asian populations. HLA-A*26 was claimed as an additional BD susceptibility marker in Japanese and Greek patients. This study was performed to test for HLA associations in HLA-B*51 negative German and Turkish BD populations.
Association of HLA-DRB1 alleles with rheumatoid arthritis in kazakh population
Автор(ы): Kuranov A. B.*Vavilov M. N.*Abisheva S. T.*Muller C. A.*Momynaliev K. T.*
Реферат: Rheumatoid arthritis (RA) is an autoimmune disease with unknown etiology affecting around 1% of the population worldwide. The present study was conducted to determine the contribution of DRB1 and DQB1 genes of HLA class II in rheumatoid arthritis in Kazakh population.
Polymorphisms of HLA-DRB1, -DQA1 and -DQB1 in inhabitants of Astana, the capital city of Kazakhstan
Автор(ы): Kuranov A. B.*Vavilov M. N.*Abildinova G. Zh.*Akilzhanova A. R.*Iskakova A. N.*Zholdybayeva E. V.*Boldyreva M. N.*Muller C. A.*Momynaliev K. T.*Pinto J.*
Реферат: Kazakhstan has been inhabited by different populations, such as the Kazakh, Kyrgyz, Uzbek and others. Here we investigate allelic and haplotypic polymorphisms of human leukocyte antigen (HLA) genes at DRB1, DQA1 and DQB1 loci in Kazakh ethic group, and their genetic relationship between word populations.
Long-term continuous spring wheat productivity in semi-arid steppe of North Kazakhstan
Автор(ы): Сулейменов М. К.*Кияс А. А.*Каскарбаев Ж. А.*
Реферат: Spring wheat is major crop in northern Kazakhstan occupying about 10 million hectares. Traditionally it is grown in summer fallow-wheat rotations with varying frequency of fallow. Fallow is used for accumulation of water, control of weeds and production of nitrates from organic matter. This practice however leads to soil degradation and should be avoided. In a long-term study at Shortandy site on black soils various fallow-wheat rotations from two year to six year were compared with continuous wheat practice. The objective of the study was to find out influence of long-term wheat growing with various frequency of summer fallow on soil fertility and economics of wheat production. The wheat yield on fallow was higher than on stubble land. However, the annualized wheat grain yield was increased with lengthening of the rotation with the highest yield in continuous wheat -88% higher as compared to alternate fallow-wheat rotation. During fifty years, the soil organic matter content decreased from 3.90 to 2.48% in two year fallow - wheat rotation as compared to 3.28% in continuous wheat. Continuous wheat is more profitable at medium and high market prices of wheat grain. Continuous wheat growing instead of summer fallow-wheat rotation is suggested. Agricultural policy supporting adoption of No-Till and application of fertilizers should be strengthened to reduce traditionally tilled summer fallow area to minimum. The reduction of tilled summer fallow area is critical to control soil erosion and degradation.
Association of cytokine gene polymorphisms with gastritis in a Kazakh population
Автор(ы): Kulmambetova G. N.*Imanbekova M. K.*Logvinenko A. A.*Sukashev A. T.*Filipenko M. L.*Ramanсulov E. M.*
Объем документа: С. 7763-7768
МРНТИ: 34.23.23*
Ключевые слова: хеликобактерная инфекция*риск развития рака желудка*полиморфизм генов цитокинов*гастрит*
Реферат: Gastritis and gastric cancer are the most common diseases in the Kazakh population. Polymorphisms in genes coding of cytokines have been played important role with gastric disease risk. The risk alleles of cytokines in patients with gastritis can predict the risk of developing gastric cancer. The aim of this study was to investigate cytokine gene polymorphisms as risk factors for the development of gastritis in a case-control study with gastritis patients and healthy individuals from the Kazakh ethnic group, living in North Kazakhstan. The data from the current study showed that the genotype IL-1B -511T/-31C-IL1-RN-2 and H. pylori infection increase risk of gastritis in the Kazakh population. That genotype combination might be a factor increasing the risk of developing gastric cancer.
Alport syndrome in a Kazakh family: a case study
Автор(ы): Zholdybayeva E. V.*Rakhimova S. E.*Baikara B. T.*Nigmatullina N. B.*Mustapayeva N. M.*Momynaliev K. T.*
Реферат: It may be concluded that Gly409Asp mutation predominantly occurs in the Asian population and it causes the development of ESRD at an early age. In addition, homozygous mutation is accompanied with hearing loss in men.
Developing PID care in Central Asia: the J Central Asia project
Автор(ы): Отарбаев Н. К.*Ковзель Е. Ф.*Тулеутаев Е.*Ибраева А.*
Объем документа:
МРНТИ: 76.29.29*
Ключевые слова: первичный иммунодефицит*ранняя диагностика ПИДа*улучшение качества жизни*
Реферат: The opportunity to improve the life quality of patients with primary immunodeficiency (PID) in the Republic of Kazakhstan and reducing the morbidity and mortality rate from PID are the main objectives of the J - project realization in the Republic of Kazakhstan. Successful project execution provides the improvement in detecting and diagnosing of PID, the prevention of PID\'s complications, the improvement of the health care of patients with PID, the creation of the Registry of the patients with PID, the implementation of the finance regulations for detection and treatment of patients with PID diseases in public health facilities, the training and professional development of medical professionals in this field.
About State financing and attracting of investments into environment protection in Republic Kazakhstan
Автор(ы): Жагыпарова А. О.*Керимбек А. К.*
Объем документа:
МРНТИ: 87.15.02*
Ключевые слова: контроль окружающей среды*экономические параметры*инвестиционная политика*экология*
Реферат: In the article there are formulated recommendations for application of various tools of environmental management regulation depending on character of influence on environment, environmental problems and purposes of a policy.
